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Lignova – Lacto – tablets



Trade name of the drug: Lignova Lacto

Active substance (INN): Lignin hydrolysis, lactulose.

Dosage form: tablets.


1 tablet contains:

Active ingredient: hydrolysed lignin (calculated per dry substance) – 355.0 mg; lactulose (calculated per 100% substance) – 120.0 mg.

Excipients: croscarmellose sodium, magnesium stearate, microcrystalline cellulose, polyvinylpyrrolidone.

Description: Dark brown tablets with white-gray spots, flat-cylindrical shape with a bevel and a rib.

Pharmacotherapeutic group: eubiotic.

ATX code: A07FA01

Pharmacological properties

Pharmacological action of the drug is caused by the properties of the constituent active ingredients – lignin and lactulose.

Lignin hydrolysis is a natural entero sorbent consisting of products of hydrolysis of wood components, has high sorption activity and nonspecific detoxifying action. Binds in the intestine and removes from the body pathogenic bacteria and bacterial toxins, drugs, salts of heavy metals, alcohol, allergens, as well as an excess of certain metabolic products, including bilirubin, cholesterol, histamine, serotonin, urea and other metabolites responsible for the development of endogenous toxicity. It is non-toxic, not absorbed, completely eliminated from the intestine within 24 hours.

Lactulose is a synthetic disaccharide whose molecule consists of galactose and fructose residues. Lactulose is not absorbed and is not hydrolyzed in the stomach and upper intestines. Lactulose released from the tablets is fermented in the large intestine as a substrate by normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli. As a result of hydrolysis of lactulose in the large intestine are formed organic acids – lactic, acetic and formic acids, which inhibit the growth of pathogens and reduce the production of nitrogen-containing toxic substances. The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulates peristalsis.

The complex action of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic states.

Indications for use

Intestinal microflora disorder, including as a result of antibiotic therapy, in the treatment of irritable bowel syndrome, hepatitis and cirrhosis, allergic diseases (atopic dermatitis, urticaria).

Methods of administration and dosages.

Inside, if necessary – after crushing, with water, an hour before a meal and taking other medicines:

  • Adults and children over 12 years – 2 – 3 tablets 3 times a day;
  • To children from 8 to 12 years – 1-2 tablets, 3 times a day;
  • Children from 3 to 7 years – 1 tablet, 3 times a day;
  • Children from 1 to 3 years – 1/2 tablet 3 times a day.

The average duration of the course of treatment is 2 to 3 weeks.

Prolonged use of the drug and repeated courses of treatment should be carried out only on the recommendation of the doctor.

Side effects

Allergic reactions to the drug components may occur, rarely – flatulence, diarrhea.


Individual intolerance to the drug, intestinal obstruction, gastrointestinal bleeding, galactosemia.

It is undesirable to use the drug in acute gastric and 12 duodenal ulcer, bowel atony.

Drug interactions

May reduce the therapeutic effect of some drugs taken at the same time orally.

Special indications

The drug may be used in combination therapy with other drugs subject to the rule of separate admission.


Symptoms: constipation, abdominal pain.

Treatment: stop taking the drug.

Form of production

Tablets №10 (1×10), №20 (2×10), №30 (3×10), №40 (4×10), №50 (5×10), №60 (6×10) (cartons), №20, №30, №40, №50, №60 (bottles).

Storage conditions

Store in a dry, dark place at temperatures under 25 ° C. Keep away from children!

Shelf life

3 years. Do not use after the expiration date.

Conditions of release from pharmacies

Released without a prescription.